Analysis Techniques and Basics of Automation and Sample Logistics (3 cr)

Objectives (course unit)

Part 1 Basics of analysis techniques
The student
- knows the operating principles, measuring methods and areas of application of the measuring devices used in clinical laboratory
- knows the basic principles related to the preparation, preservation and use of reagents, calibrators/constants and controls
- knows factors affecting the measurement quality and common sources of error
- can explain the principles and practical use of the measuring devices used in the teaching
- learns how to work in a supervised small group and to pay attention to their own and others’ occupational safety and ergonomics

Part 2. Basics of automation and sample logistics
The student
- knows the basics of automation
- gets an idea of different clinical laboratory automation solutions
- knows the operational environment of an automated laboratory
- can explain the meaning of sample logistics and how automation affects its operation

Content (course unit)

Part 1. Analysis techniques
Note: The use and measuring principle of a spectrophotometer are covered in a preliminary manner

-practical course of general laboratory practice and occupational safety
-preparation, storage and use of reagents
-reactions between the measured substance and the reagent
-calibration, control and quality management of the instruments and methods
-operating principles and sources of error in measuring instruments
-end point and kinetic measurement
-applications in clinical laboratory and special analytics; photometry measurements, potentiometric, amperometric and other electrochemical measurements
-integrations of different methods in basic analysers of chemistry and hematology
- basic concepts of flow cytometry, chromatography and mass spectrometer analysis techniques, principles and applications
-exercises in small groups, in a clinical laboratory environment and working in a small group

Part 2. Basics of automation and sample logistics
Basics of automation and fully automated clinical laboratory environment
Use of automatic analysers in analysis in clinical laboratories
Sample logistics

Assessment criteria, satisfactory (1-2) (course unit)

Part 1.
The student
- can name the operating principles and measuring methods of the more common measuring devices.
- can list some preanalytical and analytical error factors that interfere with measurements.
- needs significant guidance and support in exercises.
- pays attention to occupational safety while working in the teaching laboratory and follows given work instructions but cannot justify his/her activities.
- works within the group and gives and receives feedback.

Part 2.
The student
- knows the key concepts of the automation line and can name some of its parts.
- recognizes the importance of preanalytics and sample logistics in automation and mass production as a basis for quality.
- The written report follows the TAMK thesis reporting guidelines in general but contains many shortcomings.
- The student's reflection is repetitive
- The work has been returned within the deadline.

Assessment criteria, good (3-4) (course unit)

Part 1.
The student
- can explain the operating principles and measuring methods of the more common measuring devices.
- can list the most important preanalytical and analytical error factors that interfere with measurements and can explain their effects.
- can perform laboratory exercises under guidance.
- pays attention to occupational safety while working in the teaching laboratory, follows given work instructions and can justify his/her activities.
- works responsibly within the group and can give and receive feedback actively and constructively.

Part 2.
The student is able
- to explain the key concepts of laboratory automation.
- to describe different automation solutions and their differences.
- to justify the importance of preanalytics and sample logistics in automation and mass production as a basis for quality.
- to present a reflective and critical perspective on a given topic.
Finnish and international articles have been used as sources. The report is mainly written in accordance with TAMK's thesis reporting guidelines. The work has been returned within the deadline.

Assessment criteria, excellent (5) (course unit)

Part 1.
The student
- analyses the differences of the operating principles and measuring methods of more common measuring devices.
- can list preanalytical and analytical error factors that interfere with measurements and can explain their effect mechanisms.
- performs laboratory exercises independently, relying on given instructions and verifies issues with the teacher when necessary.
- pays attention to occupational safety while working in the teaching laboratory, follows given work instructions and can justify his/her activities.
- works constructively and responsibly within the group, gives and receives feedback actively.

Part 2.
The student is able
- to explain the key concepts of laboratory automation and various automation solutions.
- to analytically justify the importance of preanalytics and sample logistics in automation and mass production as a basis for quality.
- to present a reflective and critical perspective on a given topic, broadening his/her understanding of the subject.
Several Finnish and international articles have been used as sources. The report is written in accordance with TAMK's thesis reporting guidelines using a formal writing style. The work has been returned within the deadline.

Location and time

TAMK

Exam schedules

EXAM-tentti 18.3.-5.4.
1. uusinta 20.-24.5.
2. uusinta 3.-7.6.

Assessment methods and criteria

Analyysitekniikat:
Itsenäisten tehtävien palautus ajallaan, hyväksyttynä
Osallistuminen luentoihin ja niihin liittyvien tehtävien valmisteluun
Laboraatioon osallistuminen ja laboraation purku
Tentti

Automaatio ja näytelogistiikka:
Osallistuminen ryhmän toimintaan ja tehtävän purkuun
Vertaisarvioinnin tekeminen

Lopullinen arvosana on keskiarvo tentistä ja ryhmätyöstä.

Assessment scale

0-5

Teaching methods

Luennot
Pari- tai ryhmäesitykset
Moodletehtävät
Laboraatiot

Learning materials

Hotakainen, Lakkisto, Lempiäinen, Alagrund & Vilpo. Laboratoriolääketiede : kliininen kemia ja hematologia. 5. painos. Helsinki: Kandidaattikustannus, 2023. Saatavilla e-kirjana.
(luvut 1-3, 7 ja 9)

Luentomateriaalit
Muut opettajan jakamat materiaalit

Student workload

Analyysitekniikat 2op:
Luennot ja niihin valmistautuminen 20 h
Laboraatiot 4 h
Tehtävät 6 h
Tentti 2 h
Itsenäinen työskentely 22h

Automaatio ja näytelogistiikka 1op:
Luento ja ohjaustunti 2-4h
Tehtävän purku 4h
Yhteinen työskentely n. 20h

Content scheduling

Osa 1, Analyysitekniikat 17.1.-8.3.
Osa 2, Automaatio ja näytelogistiikka 7.3.-5.4.

Completion alternatives

Ei valinnaisia tapoja

Practical training and working life cooperation

-

Further information

Student has acceptably completed Practical course of general laboratory practice 7B00EG12 study module.