Molecular Biology and GeneticsLaajuus (7 cr)

Objectives

Student is able to..
- explain the key methods used in molecular biology and perform practical exercises under supervision
- describe the basics of recombinant DNA technology and the main applications
- understand the basics of genetics and associated research methods
- define the different steps of cloning
- define the different stages of nucleic acid purification
- describe the basics of amplification methods
- understand the basics of hybridization methodsdefine the basic concepts of genetics
- describe the different stages of chromosomal analysis and karyotyping
- describe the research methods used in clinical applications
- define the methods used in fetal diagnostics
- learn to consider the ethical aspects of fetal diagnostics

Content

Molecular biology (synthesis of macromolecules, isolation and purification of nucleic acids, amplification methods, electrophoresis)
Recombinant DNA technology
Hybridization methods
Methods used in genetics
Key methods and applications used in diagnostics, research and biotechnology
Chromosomes
Chromosomal analysis
FISH, Multicolor FISH
Genetics of cancer and associated research methods
Fetal diagnostics, ethical aspects and choice of values

Prerequisites

The student must have passed 7B00BB98 Basic Theory and Basic Methods of Molecular Biology before the course 7B00BO92 Clinical training in Molecular Laboratory

Further information

The course includes clinical training in the university of applied sciences' teaching laboratory